Gain-of-Function Mutations in TRPM4 Cause Autosomal Dominant Isolated Cardiac Conduction Disease
نویسندگان
چکیده
منابع مشابه
Gain-of-function mutations in TRPM4 cause autosomal dominant isolated cardiac conduction disease.
BACKGROUND Isolated cardiac conduction block is a relatively common condition in young and elderly populations. Genetic predisposing factors have long been suspected because of numerous familial case reports. Deciphering genetic predisposing factors of conduction blocks may give a hint at stratifying conduction block carriers in a more efficient way. METHODS AND RESULTS One Lebanese family an...
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ژورنال
عنوان ژورنال: Circulation: Cardiovascular Genetics
سال: 2010
ISSN: 1942-325X,1942-3268
DOI: 10.1161/circgenetics.109.930867